Publications
2023
Sorensen-Turpin, C.G., Sloan, D., LaForest, M., Uehlein-Klebanow, L., Mitchell, D., Severson, A. F., Bembenek, J.N. (2023). Securin Regulates the Spatiotemporal Dynamics of Separase. bioRxiv 2023.12.12.571338; doi: https://doi.org/10.1101/2023.12.12.571338. PMID: 38168402.
Camp, O.G., Bembenek, J.N., Goud. P.T. Awonuga, A.O., Abu-Soud, H.M. (2023). The implications of insufficient zinc on the generation of oxidative stress leading to decreased oocyte quality. Reprod. Sci. https://doi.org/10.1007/s43032-023-01212-0. PMID: 36920672.
2022
Fielder, S.M., Rosenfeld, J.A., Burrage, L.C., Murdoch, D., Bembenek, J.N., Hoang, H., Baldridge, D., Silverman, G., Undiagnosed Diseases Network, Schedl, T., and Pak, S.C. (2022). Functional analysis of a novel de novo variant in PPP5C associated with microcephaly and developmental delay. Mol Genet Metab. May;136(1):65-73. https://doi.org/10.1016/j.ymgme.2022.03.007.
2021
Sloan, D.E., Bembenek, J.N. (2020). Endogenous expression and localization of HIS-72::mTurquoise2 in C. elegans. μPub. Bio. https://doi.org/10.17912/micropub.biology.000471.
2020
Bai, X.*, Melesse, M.*, Sorensen Turpin, C.G.*, Sloan, D.*, Chen, C.Y., Wang, W.C., Lee, P.Y., Simmons, J.R., Nebenfuehr, B., Mitchell, D., Klebanow, L.R., Mattson, N., Betzig, E., Chen, B.C., Cheerambathur, D.K., Bembenek, J.N. (2020). Aurora B Functions at the Apical Surface after Specialized Cytokinesis During Morphogenesis in C. elegans. Development, 147: dev181099 doi: 10.1242/dev.181099. *equal contributions
Rathbun, L.I., Alijiboury, A., Bai, X., Hall, N., Manikas, J., Amack, J., Bembenek, J.N., Hehnly, H. PLK1- and PLK4-Mediated Asymmetric Mitotic Centrosome Size and Positioning in the Early Zebrafish Embryo. (2020). Curr. Bio., https://doi.org/10.1016/j.cub.2020.08.074.
Borja, L.B., Soubigou, F., Taylor, S.J.P., Bringas, C.F., Budrewicz, J., Lara-Gonzalez, P., Sorensen Turpin, C.G., Bembenek, J.N., Cheerambathur, D.K., Pelisch, F. Bub-1 Targets PP2A:B56 to Regulate Chromosome Congression During Meiosis I in C. elegans Oocytes. eLife. https://elifesciences.org/articles/65307.
Sloan, D.E., Bembenek, J.N. (2020). Endogenous expression and localization of CAV-1::GFP in C. elegans. μPub. Bio. 10.17912/micropub.biology.000311.
2019
Del Castillo, U., Gnazzo, M.M., Sorensen Turpin, C.G., Semaya, E., Lam, Y., De Cruz, M.A., Bembenek, J.N., Hall, D.H., Riggs, B., Gelfand, V.I., Skop, A.R. (2019). Conserved role for Ataxin-2 in mediating ER dynamics. Traffic, DOI: 10.1111/tra.12647.
Melesse, M. and Bembenek, J.N. (2019). Cracking the Eggshell: A novel link to intracellular signaling. Dev. Bio., 453(1), 107-109.
2018
Avasthi, P., Soragni, A., Bembenek, J.N. (2018). Leveraging Journal Clubs for Peer Review Training and Preprint Feedback. eLife, 7:e38532. DOI: 10.7554/eLife.38532.
Melesse, M., Sloan, D.E., Benthal, J.E., Caylor, Q., Gosine, K., Bai, X., Bembenek, J.N. (2018). Genetic Identification of Separase Regulators in Caenorhabditis elegans. G3, 8(2), 695-705. DOI: 10.1534/g3.117.300298
Melesse, M., Bembenek, J.N., Zhulin, I.B. (2018). Conservation of the Separase Regulatory Domain. Bio. Dir. 13:7. DOI: 10.1186/s13062-018-0210-0
Bai, X. and Bembenek, J.N. (2018). Orchestrating Early Embryonic Divisions. Mol. Reprod. Dev. 85(2):86. DOI: 10.1002/mrd.22874
2017
Bai, X. and Bembenek, J.N. (2017). Protease Dead Separase Inhibits Chromosome Segregation and RAB-11 Vesicle Trafficking. Cell Cycle. 16(20): 1902-1917. DOI: 10.1080/15384101.2017.1363936
Bembenek, J.N., Meshik, X., Tsarouhas, V. (2017). Meeting Report: Cellular Dynamics: Membrane-Cytoskeleton Interface. J. Cell Sci. 130(17): 2775-2779. DOI: 10.1242/jcs.208660
2014
Chen, B.C., Legant, W.R., Kai, W., Shao, L., Milkie, D.E., Davidson, M.W., Janetopoulos, C., Wu, X.S., Hammer, J.A., Liu, Z., English, B.P., Mimori-Kiyosue, Y., Romero, D.P., Ritter, A.T., Lippincott-Schwartz, J., Fritz-Laylin, L., Mullins, R.D., Mitchell, D.M., Bembenek, J.N., Raymann, A.C., Böhme, R., Grill, S.W., Wang, J.T., Seydoux, G., Tulu, U.S., Kiehart, D.P., Betzig, E. (2014). Lattice Light Sheet Microscopy: Imaging Molecules to Embryos at High Spatiotemporal Resolution. Science, 346, 1257998. DOI: 10.1126/science.1257998
*Awarded AAAS Newcomb Cleveland Prize for the most outstanding research article published in Science, highlighted in several media and journal publications (including National Geographic).
Mitchell, D.M., Uehlein, L.R., Bembenek, J.N. (2014). Protease-Dead Separase is Dominant Negative in the C. elegans Embryo. PLoS ONE 9(9): e108188. DOI: 10.1371/journal.pone.0108188
2013
Bembenek, J.N.*, Verbrugghe, K.J.C.*, Khanikar, J., Csankovszki, G., Chan, R.C. (2013). Condensin I and the spindle midzone prevent furrow regression induced by chromosome mis-segregation in C. elegans embryos. Curr. Bio. 23, 937-946. DOI: 10.1016/j.cub.2013.04.028
*These authors contributed equally to this work.
Schvarzstein, M., Pattabiraman, D., Bembenek, J.N., and Villeveuve, A.M. (2013). Meiotic HORMA domain proteins prevent untimely centriole disengagement during C. elegans spermatocyte meiosis. PNAS 110, E898-E907. DOI: 10.1073/pnas.1213888110
*Recommended by Robert Herman in F1000Prime.
2011
Richie, C.T.*, Bembenek, J.N.*, Chestnut, B., Furata, T., Schumacher, J.M., Anderson, D.E. and Golden, A. (2011). Protein Phosphatase 5 is a Negative Regulator of Separase Function During Cortical Granule Exocytosis in C. elegans. J. Cell Sci. 124, 2903-2913. DOI: 10.1242/jcs.073379
*These authors contributed equally to this work.
Collette, K.S., Petty, E.L., Golenberg, N., Bembenek, J.N., and Csankovszki, G. (2011). Different Roles for Aurora B in Condensin Targeting During Mitosis and Meiosis. J. Cell Sci. 124, 3684-3694. DOI: 10.1242/jcs.088336
2010
Bembenek, J.N., White, J.G. and Zheng, Y. (2010). A Role for Separase in the Regulation of RAB-11-positive Vesicles at the Cleavage Furrow and Midbody. Curr. Biol. 20(3), 259-264. DOI: 10.1016/j.cub.2009.12.045
Featured in dispatch by Sandra López-Avilés and Frank Uhlmann.
2007
Bembenek, J.N., Richie, C. T., Squirrell, J.M., Campbell, J.M., Elieiri, K.W., Poteryaev, D., Spang, A., Golden, A., and White, J.G. (2007). Cortical Granule Exocytosis in C. elegans is Regulated by Cell Cycle Components Including Separase. Development 134, 3837-3848. DOI: 10.1242/dev.011361
Evaluated by Jonathan Hodgkin and Michel Labouesse for Faculty of 1000.
2005
Bembenek, J., Kang, J., Kurischko, C., Li, B., Raab, J.R., Belanger, K.D., Luca F.C., and Yu, H. (2005). Crm1-Mediated Nuclear Export of Cdc14 is Required for the Completion of Cytokinesis in budding yeast. Cell Cycle 4: 961-971. DOI: 10.4161/cc.4.7.1798
2004
Wang, W.Q., Bembenek, J., Gee, K.R., Yu, H., Charbonneau, H., and Zhang, Z.Y. (2004). Kinetic and Mechanistic Studies of a Cell Cycle Protein Phosphatase Cdc14. J. Biol. Chem. 279: 30459-30468. DOI: 10.1074/jbc.M402217200
2003
Bembenek, J., and Yu, H. (2003). Regulation of Cdc14: Pathways and Checkpoints of Mitotic Exit. Frontiers in Bioscience 8: d1275-1287. DOI: 10.2741/1128
2001
Bembenek, J., and Yu, H. (2001). Regulation of the Anaphase-Promoting Complex by the Dual-Specificity Phosphatase, Human Cdc14A. J. Biol. Chem. 276: 48237-48242. DOI: 10.1074/jbc.M108126200
Cover image, evaluated by Frederick R. Cross for Faculty of 1000.